Symbol
Name
ID

Il4ra
interleukin 4 receptor, alpha
MGI:105367

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Increased circulating IgA level	Increased circulating IgG level	Decreased circulating antibody level	Paraproteinemia	Anemia	Multiple myeloma	Elevated erythrocyte sedimentation rate	Splenomegaly
Disease(s) Associated with IL4R	Increased circulating IgA level	Increased circulating IgG level	Decreased circulating antibody level	Paraproteinemia	Anemia	Multiple myeloma	Elevated erythrocyte sedimentation rate	Splenomegaly
multiple myeloma
rheumatoid arthritis

Mouse Phenotypes

impaired macrophage chemotaxis

decreased T cell proliferation

increased eosinophil cell number

decreased T-helper 2 cell number

increased monocyte cell number

abnormal T-helper 2 cell morphology

abnormal microglial cell morphology

decreased IgE level

increased IgE level

decreased IgG1 level

increased IgG2a level

increased IgG level

abnormal T-helper 2 physiology

abnormal macrophage physiology

abnormal macrophage activation involved in immune response

Availability

Mouse Genotype

Il4ra^M1Btlr/Il4ra^M1Btlr

Il4ra^M2Btlr/Il4ra^M2Btlr

Il4ra^tm1Fbb/Il4ra^tm1Fbb

Il4ra^tm1Sz/Il4ra^tm1Sz

Il4ra^tm1Tch/Il4ra^tm1Tch

Il4ra^tm2Tch/Il4ra^tm2Tch

Il4ra^tm3.1Tch/Il4ra^tm3.1Tch

Il4ra^tm1Fbb/Il4ra^tm2Fbb
Lyz2^tm1(cre)Ifo/Lyz2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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